Imunologie - din amintiri

OK... vad ca ai citit mult, ca pui suflet, te admir pentru modul in care iti aperi punctul de vedere, dar eu nu pot sa cred in teoriile conspirationiste. Nu pot. Dar multumesc pentru timpul pe care l-ai acordat acestui subiect (si mie)!

Hai sa raspund si eu desi nu am fost intrebat.
Hai sa intreb desi am mai intrebat.


Am hotarat sa nu ne vaccinam bebeii cu vaccinurile incluse in schema nationala "obligatorie" si sa optam pt homeopatie.Pareri contra? Pro ? Mai este cineva pe aici cu asemenea experiente,eventual cu bebei care acum sunt copii mai mari ?
Cei mai multi homeopati titrati sunt de negasit tocmai cand bebelul are febra sau necesita o interventie urgenta.
Din cate stiu, debutul interventiei homeopate inseamna o anamneza amanuntita, un interviu pt stabilirea profilului pacientului, pt ca, in functie de aceste particularitati sa se prescrie un remediu particularizat. Intrebari/propuneri tematice :
1)Cum se explica atunci liste, intocmite de homeopati, continand muuulte remedii? Accept ca rapunsul organismului difera si in acest caz trebuie prescris un alt remediu.
2)Cei mai titrati homeopati nu raspund tocmai cand ai mai mare nevoie de ei.Daca homeopatia se bazeaza pe acea anamneza initiala, cat de eficient/viabil este sa apelezi,in caz de urgenta, la un alt homeopat ?

Copilul tau daca nu-i faci vaccinul nu va suferi prea tare, mai are ceva imunitate de la parintii care au facut deja acele vaccinuri.

Insa copii lui vor avea un risc de expunere marit (a fost un episod si in Doctor House legat de astea).

@luuc: Poți continua discuția despre homeopatie la Homeopatie și tratamente alternative!

Imunitatea provenită de la părinții vaccinați ține câteva luni.

House e ficțiune. Cum au copiii copiilor nevaccinați risc de expunere mărit?

Fa vaccinurile obligatorii si nu-ti complica viata!

Sunt testate de ani de zile si sunt minimul garantat de protectie impotriva polio si alte boli cumplite si nu pentru virusi mutanti precum gripele astea.

Copilul tau daca nu-i faci vaccinul nu va suferi prea tare, mai are ceva imunitate de la parintii care au facut deja acele vaccinuri.

Insa copii lui vor avea un risc de expunere marit (a fost un episod si in Doctor House legat de astea).

antigen said:

Poti detalia sau trimite un link, te rog ?!

"The table documents that all of the 30 viral proteomes under analysis have high and wide pentapeptide overlapping to the human proteome. Only a limited number of viral pentamers are unique to the viruses, with no counterpart in the human proteome. The overlapping extent (in terms of percentage of unique viral 5-mers which
occur in the human proteome, see column 6 in Table 4) is rarely less than 90%. That means that almost 90% of the viral pentamer peptides are widely, intensively and repeatedly scattered throughout the human proteome.
[..]
Given the ample literature documentation and research data in support of the critical role exerted by pentapeptide modules in cell biology as well in antigen/antibody immunorecognition ([17], and Refs. therein), the data of Table 4 are impressive. They become even more significant, if possible, when compared to the control data obtained for inter-human pentapeptide overlapping illustrated in Table 5. [..]
in the context of the physio(patho)logical relationships between viruses and humans, it is mandatory to observe that short-peptide motifs can exert a central role in cell adhesion, signal transduction, hormone activity, regulation of transcript expression, and enzyme activity [3,9,10,14,15,17]. Likewise, the antigen-antibody recognition process can reductionistically be circumscribed to interacting modules of five amino acid residues which, therefore, appear to be sufficient structural immunological determinants ([11-13,17] and Refs. therein). Consequently,we notice that the data shown here call into question the possibility of a direct causal association between virus-host sharing of amino acid motifs and incitement of autoimmune reactions [20].

" Theoretically, the cross-reactivity potential in using viral antigens is equal to zero, by being 1 in 205 (that is, one out 3,200,000), the mathematical probability of 20 amino acids occurring in five identical residues between two proteins. Likewise, the theoretical probability of 20 amino acids occurring in six identical residues between two proteins is 1 in 206, that is equal to 1 out 64,000,000.

However, conflicting with theoretical data, the numbers reported in Table 1 show the highest probability of cross-reactions, given the highest number of perfect exact matches between the viral and human proteomes. This contrast between theoretical versus actual values in the number of peptide overlaps is a powerful warning incum-bent on the future of vaccine development and delivery.

Analysis of the quantitative results reported in Table 1 and the qualitative data exposed in Table 2 indicate that the logical consequence of cross-reactions following anti-HPV vaccine administration may be possibly represented by alterations in epithelial cell proliferation (Olsen et al., 1989), obesity and subnormal rate of growth (Goddard et al., 1995); AlzheimerŽs disease (Rademakers et al., 2004); increased atherogenic potential (Dong et al., 2006); bone disorders; sensorineural deafness; ocular disorders including juvenile cataract, myopia, strabismus, retinal degeneration and detachment, and chronic uveitis (Annunen et al., 1999); alteration of differentiation, proliferation and apoptosis (Sugaya et al., 1997); alterations in myeloid cell nuclear differrentiation (Briggs et al., 1992); alteration in brain-specific regulation of cell proliferation (Xe et al., 1989), to cite only a few.

In conclusion, it seems that vaccine safety monitoring becomes more and more important with new vaccines, intensive vaccine recommendations, and new expanded immunization initiatives. In this scenario, the molecular antigen dissection described in the present paper may be the basic platform for avoiding possible cross-reactive hot spots and achieving high standards of safety (Kanduc, 2009)."

BACKGROUND: The potential adverse events associated with vaccination for infectious diseases underscore the need for effective analysis and definition of possible vaccine side effects. Using the HPV16 proteome as a model, we quantified the actual and theoretical risks of anti-HPV16 vaccination, and defined the potential disease spectrum derived from concomitant cross-reactions with the human organism. METHODS: We searched the primary sequence of the HPV16 proteome for heptamer aminoacid sequences shared with human proteins using the Protein International Resource database. RESULTS: The human proteome contains 82 heptapeptides and two octapeptides found in HPV16. The viral matches are spread among proteins involved in fundamental processes, such as cell differentiation and growth and neurosensory regulation. The human proteins containing the HPV16-derived heptamers include cell-adhesion molecules, leukocyte differentiation antigens, enzymes, proteins associated with spermatogenesis, transcription factors, and neuronal antigens. The number of viral matches and their locations make the occurrence of side autoimmune cross-reactions in the human host following HPV16-based vaccination almost unavoidable. CONCLUSIONS: Any antigen-based vaccine needs to be carefully and thoroughly designed and critically screened for potential side effects by comparing sequence similarity at the molecular level.

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