Aulin - PERICOL!

vulpitza2004, on May 18 2009, 22:55, said:

Cumva ai analize la ficat si dinainte de a folosi Aulin? Ca altfel nu ai cum sa faci comparatie.

vulpitza2004, on May 18 2009, 22:55, said:

Problema nu este ce spune presa, ci mai degraba ce spune politia si sistemul de sanatate din America si Japonia.
In acest caz politia spune: industria farmaceutica a platit organele de control din Italia pentru a putea vinde Aulinul.
Iar sistemul de sanatate SUA si Japonia spune: la noi in tara nu a fost acceptat niciodata Aulinul (nu l-au puns la vanzare nici macar o zi).
Cam atat

Ei au au avut Vioxx .

Poate ca era prea scump ca sa-l introduca in Romania?

A fost si in Romania si mergea chiar binisor ca vanzari. La noi n-a murit nimeni din el din 2 motive: 1) dupa Cernobal nu ne mai omoara nimic si 2) nimeni nu avea atatia bani ca sa ia 2 ani de zile neintrerupt Vioxx ca prostalaii de americani.

Edited by gamezcdr, 26 May 2009 - 11:59.

Deci daca la ei au permis Vioxx dar n-au permis Aulin... va las pe voi sa trageti concluzia cat de bun este Aulinul

Edited by lymphor, 29 May 2009 - 07:15.

Daca firma producatoare n-a trimis dosar sa-l inregistreze in SUA era chiar culmea sa-l inregistreze .

Ia uite aici ce zice un nene:
A prime example of a drug that should have been approved by the FDA years ago is a COX-2 inhibitor called nimesulid. Americans suffered from arthritis pain and cartilage degeneration while nimesulid was long-ago approved in other countries. Americans now pay outrageously high prices for FDA-approved COX-2 inhibitors and American cancer patients are dying because this class of drug is not yet approved to treat cancer. Nimesulid was patented way back in 1971, but Americans had to wait for another COX-2 inhibitor called Celebrex to be approved in December 1999. Some studies indicate that nimesulid is safer than Celebrex or Vioxx. Nimesulid may also be more effective in the adjuvant treatment of cancer than Celebrex or Vioxx. It costs about $125.00 a month for Celebrex or Vioxx, yet nimesulid can be obtained in Europe for only $22.00 per month. It is unconscionable that U.S. citizens were denied access to COX-2 inhibitors for so long and now have to pay an average of five times more for this class of medication.
Ia uite ce zice EMEA (FDA al Europei)
In 2002 nimesulide benefit/risk profile was reviewed by the EMEA following decision to temporarily suspend the drug from the market in March 2002, in relation to the reporting of hepatic adverse effects in patients apparently treated with nimesulide. It was later demonstrated that the occurrence of hepatic reactions with nimesulide is similar to that of any other NSAIDs as confirmed by a study published by the British Medical Journal in 2003
On August 1, 2003 the Committee for Proprietary Medicinal Products (CPMP) of the EMEA reported that the benefit/risk profile of nimesulide containing medicinal products (Aulin, Mesulide, Nimed and associated product names) for systemic and topical use is favourable and that Marketing Authorisations should be maintained/granted. The CPMP recommended to restrict the use of nimesulide to the indications of treatment of acute pain, symptomatic treatment of painful osteoarthritis and primary dysmenorrhoea for the systemic formulations and symptomatic relief of pain associated with sprains and acute tendinitis for the topical formulation. [2]
On September 21, 2007 the EMEA released a press release on their review on the liver-related safety of nimesulide. The EMEA has concluded that the benefits of these medicines outweigh their risks, but that there is a need to limit the duration of use to ensure that the risk of patients developing liver problems is kept to a minimum. Therefore the EMEA has limited the use of systemic formulations (tablets, solutions, suppositories) of nimesulide to 15 days. [7]

Edited by gamezcdr, 29 May 2009 - 19:22.

lymphor, on 29th May 2009, 08:14, said:

concluzia e alta : Vioxx-ul e made in USA.

Paaai!...
1. "Pe scurt: Aulinul este interzis in Japonia si Statele Unite, a fost interzis in Spania si in Finlanda in 2002 dupa 1 caz de deces si 66 de cazuri de daune hepatice, si in Irlanda a fost interzis in 2006 dupa ce 6 pacienti au fost nevoiti sa faca transplant de ficat."

in SUA aulin/nimesulidele au fost aprobate si impactul a fost excelent lasand fara cote de piata mari concerne. FDA a aprobat punerea lui pe piata fara nici cea mai mica ezitare. Ce-s alea "daune hepatice"?
de fapt nici nu esti medic
2. In Italia au fost arestate 8 persoane (dintre care 2 dintre directori cei mai importanti) a lui AIFA, asociatia care se ocupa cu controlul si aprobarea medicamentelor in Italia. In scandal mai sint cercetati directorul general si cativa manageri AIFA, manageri Bayer, manageri Glaxo, cercetatori si politici.
Practic: functionari si sefi de la AIFA primeau lunar mita pentru ca sa treaca cu ochiul si sa permita vanzarea in Italia a Aulinului si a altor medicamente."

interesant ca dupa ce ai pomenit de coruptie si corupti mai tarziu ai uitat de ceilalti implicati in scandal si ai avut o treaba doar cu aulinul.
Ce sunt acei "politici" de care pomenesti? ce persoane sunt alea?


4. "Problema nu este ce spune presa, ci mai degraba ce spune politia si sistemul de sanatate din America si Japonia.
In acest caz politia spune: industria farmaceutica a platit organele de control din Italia pentru a putea vinde Aulinul.
Iar sistemul de sanatate SUA si Japonia spune: la noi in tara nu a fost acceptat niciodata Aulinul (nu l-au puns la vanzare nici macar o zi).
Cam atat"

He he! In SUA a fost aprobat! S U R P R I Z A ! ! !


Iti recomand sa citesti comunicatele EMEA si FDA in ce priveste utilizarea nimesulidelor!

Ei sunt forurile cele mai competente si la care chiar tu te raportezi si le crezi Dumnezeu pe pamant in domeniul medicamentelor.

Edited by adadoi, 20 October 2010 - 07:56.

Atata vreme cat un medicament este luat cf prescriptiei / indicatiilor medicale nu exista nici un pericol, indiferent daca este Aulin, Movalis sau alt calmant. Am luat si eu si nu am patit nimic. Sper sa nu am nevoie, insa daca ar fi, voi lua asa cum zice medicul.
Si evident, ca daca cineva stie ca are probleme care nu ii permit sa ia astfel de calmante, atunci sa ii spuna medicului si se va gasi o alternativa cu siguranta.

Si nu va mai luati dupa toate tampenile care apar pe net, cu studii facute de cercetatorii lu peste prajit.

Anny, on 6th April 2010, 11:45, said:

Nimesulid(AULIN) poate fi foarte daunator pentru ficat,dar luat in cantitati mari.In cantitati prescrise de medic este unul dintre cele mai bune antiinflamatoare care inca mai exista pe piata.Tatal meu este farmacist primar si se trateaza cu NIMESULID(aulin),la fel si mama.

[quote name='gamezcdr' post='6557907' date='29th May 2009, 20:22']Ia uite aici ce zice un nene:
A prime example of a drug that should have been approved by the FDA years ago is a COX-2 inhibitor called nimesulid. Americans suffered from arthritis pain and cartilage degeneration while nimesulid was long-ago approved in other countries. Americans now pay outrageously high prices for FDA-approved COX-2 inhibitors and American cancer patients are dying because this class of drug is not yet approved to treat cancer. Nimesulid was patented way back in 1971, but Americans had to wait for another COX-2 inhibitor called Celebrex to be approved in December 1999. Some studies indicate that nimesulid is safer than Celebrex or Vioxx. Nimesulid may also be more effective in the adjuvant treatment of cancer than Celebrex or Vioxx. It costs about $125.00 a month for Celebrex or Vioxx, yet nimesulid can be obtained in Europe for only $22.00 per month. It is unconscionable that U.S. citizens were denied access to COX-2 inhibitors for so long and now have to pay an average of five times more for this class of medication.
Ia uite ce zice EMEA (FDA al Europei)
In 2002 nimesulide benefit/risk profile was reviewed by the EMEA following decision to temporarily suspend the drug from the market in March 2002, in relation to the reporting of hepatic adverse effects in patients apparently treated with nimesulide. It was later demonstrated that the occurrence of hepatic reactions with nimesulide is similar to that of any other NSAIDs as confirmed by a study published by the British Medical Journal in 2003
On August 1, 2003 the Committee for Proprietary Medicinal Products (CPMP) of the EMEA reported that the benefit/risk profile of nimesulide containing medicinal products (Aulin, Mesulide, Nimed and associated product names) for systemic and topical use is favourable and that Marketing Authorisations should be maintained/granted. The CPMP recommended to restrict the use of nimesulide to the indications of treatment of acute pain, symptomatic treatment of painful osteoarthritis and primary dysmenorrhoea for the systemic formulations and symptomatic relief of pain associated with sprains and acute tendinitis for the topical formulation. [2]
On September 21, 2007 the EMEA released a press release on their review on the liver-related safety of nimesulide. The EMEA has concluded that the benefits of these medicines outweigh their risks, but that there is a need to limit the duration of use to ensure that the risk of patients developing liver problems is kept to a minimum. Therefore the EMEA has limited the use of systemic formulations (tablets, solutions, suppositories) of nimesulide to 15 days. [7][/quote]
Da, se pare ca au fost niste interese economice in favoarea Vioxx-ului.
Multumesc pt info

[quote name='tavistan' post='6819713' date='24th July 2009, 00:39']in SUA aulin/nimesulidele au fost aprobate si impactul a fost excelent lasand fara cote de piata mari concerne. FDA a aprobat punerea lui pe piata fara nici cea mai mica ezitare.[/quote]
Se pare ca nu (de citit ultima Q&A):
[url="http://www.nimesulide.net/Institutional.aspx?Pagina=QeA&SM=QeA&Lingua=EN"]http://www.nimesulide.net/Institutional.as...A&Lingua=EN[/url]

[quote name='tavistan' post='6819713' date='24th July 2009, 00:39']Ce-s alea "daune hepatice"?[/quote]
Ce nu intelegi?

[quote name='tavistan' post='6819713' date='24th July 2009, 00:39']de fapt nici nu esti medic.[/quote]
1. Nu iti permit sa ma calomniezi si sa ma jignesti.
2. N-am spus niciodata ca sunt medic.

[quote name='tavistan' post='6819713' date='24th July 2009, 00:39']interesant ca dupa ce ai pomenit de coruptie si corupti mai tarziu ai uitat de ceilalti implicati in scandal si ai avut o treaba doar cu aulinul.[/quote]
Ceilalti implicati in scandal au fost arestati si izolati.
Aulinul insa este inca "liber" in Romania (si nu numai)

[quote name='tavistan' post='6819713' date='24th July 2009, 00:39']Ce sunt acei "politici" de care pomenesti?[/quote]
Mi-a scapat un "oameni" dar toata lumea a inteles sensul propozitiei, numai tu te prefaci ca n-ai inteles.



Deoarece nu reusesc sa mai introduc citate in acest raspuns de acum incolo o sa trec cu albastru mesajele scrise de ceilalti useri.

[quote name='tavistan' date='24th July 2009, 00:39' post='6819713']
He he! In SUA a fost aprobat! S U R P R I Z A ! ! !

Se pare ca nu (a se citi ultimul Q&A):
[url="http://www.nimesulide.net/Institutional.aspx?Pagina=QeA&SM=QeA&Lingua=EN"]http://www.nimesulide.net/Institutional.as...A&Lingua=EN[/url]


Iti recomand sa citesti comunicatele EMEA si FDA in ce priveste utilizarea nimesulidelor!

Iti recomand sa citesti ultimul Q&A de pe site-ul asta:
[url="http://www.nimesulide.net/Institutional.aspx?Pagina=QeA&SM=QeA&Lingua=EN"]http://www.nimesulide.net/Institutional.as...A&Lingua=EN[/url]


Ei sunt forurile cele mai competente si la care chiar tu te raportezi si le crezi Dumnezeu pe pamant in domeniul medicamentelor.

Nu m-am raportat la ele ca la Dumnezeu pe pamant, mai ales ca Dumnezeu nu se contrazice singur asa cum au facut EMEA si FDA in mai multe ocazii.



[quote name='Anny' date='6th April 2010, 11:45' post='8036509']
Atata vreme cat un medicament este luat cf prescriptiei / indicatiilor medicale nu exista nici un pericol,

Da sigur, asa cum era Aulinul acum cativa ani


Am luat si eu si nu am patit nimic.

Ai analize facute inainte si dupa administrare?


Si nu va mai luati dupa toate tampenile care apar pe net, cu studii facute de cercetatorii lu peste prajit.

Sper ca nu vorbesti despre articolul tradus de mine, mai ales ca acela nu este un studiu

Edited by adadoi, 20 October 2010 - 08:00.
citare mesaje sterse de moderator

Am luat aulin (plicuri) vreo 4-5 zile fara nici un rezultat, nici bine nici rau.

pentru cei care cred ca cineva plateste mita pentru a putea vinde medicamente impotriva durerii puternice care costa 2,5 euro este complet paralel cu realitatea.Orice medicament poate avea anumite efecte advese ce pot avea complicatii. Dar daca e cineva pe aici care are putin simt al realitati si-ar da usor seama ca singura posibila conspiratie este impotriva Aulin deoarece este un medicament ieftin care face treaba altora de genu "Diclofenac" tablete care in loc de 2,5 euro costa undeva pe la 30-50 euro.
Pentru a nu pare lipsiti de simtul realitati nu mai veniti cu teorii cum ca cineva plateste ca sa vanda medicamente ieftine impotriva dureri. Deoarece daca nu exista medicamente ieftine impotriva dureri oricum oameni vor lua ceva sa le calemeze durerile si vor avea doar medicamente scumpe sau leacuri babesti.

Unde e diclofenac-ul 30 de euro?

oaspetele, on 15 mai 2014 - 04:35, said:

Nici in cosmaruri
Diclofenacul in UK e pana intr-o lira, cutie cu 28 pastile. Acum am verificat la farmaciile lor.

lex404, on 15 mai 2014 - 04:56, said:

Cand? Unde? Ce concentratie? Ce marca? Credeam ca MHRA a zis asa:

Maximum strength: 25mg
Maximum dose:  25mg
Maximum daily dose: 75mg
Maximum duration of treatment: 3 days
Maximum pack size: 225mg of product

headlikeahole, on 01 iulie 2014 - 13:36, said:

http://www.pharmacy2...clofenac sodium


Uite, sa nu zici ca vorbesc gogosi. E prescription Only, dar e sub o lira!