Windows Defender is turned off

ma cam indoiesc caci nu ar avea.

...there are services in an Anti Virus that are not fulfilled by MBAM.
    It does not target scripted malware
    It does not target document files
    It does not target media files
    It is still incapable of of removing malicious code that had been prepended, appended or cavity injected into legitimate files such as by a file infecting virus or by a trojan that trojanizes legitimate files ( aka; patches ).
    It is not MAPI and/or VIM compliant nor does it offer a POP/IMAP Proxy Service.
    It does not handle legacy malware because Malwarebytes personnel culls it database periodically and only tragets what they call Zero Day malware. Malware that is fresh and new Today and not something that was more prevalent a year or two ago.
    An anti virus may intercept email and it will then decode the MIME and scan the body and attachments and flag the email as a Phish, Fraud or some other malicious content. MBAM may have and Anti Exploit module but that is for software exploitation. It does NOTHING for Social Engineering which is the Human Exploit such as those demonstrated in Fraud and Phishing emails.
    If one ONLY depends on MBAM they lose the warnings made by traditional anti virus applications that performs scanning the file types MBAM does not target. They lose a layer of protection that an AV provides. So if one has a folder of Wimad trojans and only MBAM is installed, the computer user will never know. However if they had a fully installed Anti Virus solution performing "On Access" and "On Demand scanning on ALL file types, there would be a warning the files are malicious. This an indicator. MBAM will only protect one IFF they try to play a media file and it attempts some not standard media player function. MBAM will not tell you that is a malicious HyperText Application, or that XLS uses malicious macros or that MP3 is a Wimad or that web site has an Embedded IFrame.
That indicates to me that Malwarebytes 3.0 Premium is still better served as an adjunct anti-malware solution to complement and strengthen your protection when utilizing a traditional anti-virus solution.